Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity

The gradual accumulation of mutations by any of a number of mutational processes is a major driving force of divergence and evolution. Here, we investigate a potentially novel mutational process that is based on the activity of members of the AID/APOBEC family of deaminases. This gene family has bee...

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Detalles Bibliográficos
Autores principales: Pinto, Yishay, Gabay, Orshay, Arbiza, Leonardo, Sams, Aaron J., Keinan, Alon, Levanon, Erez Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864454/
https://www.ncbi.nlm.nih.gov/pubmed/27056836
http://dx.doi.org/10.1101/gr.199240.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864454/
https://www.ncbi.nlm.nih.gov/pubmed/27056836
http://dx.doi.org/10.1101/gr.199240.115

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