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Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity
The gradual accumulation of mutations by any of a number of mutational processes is a major driving force of divergence and evolution. Here, we investigate a potentially novel mutational process that is based on the activity of members of the AID/APOBEC family of deaminases. This gene family has bee...
Autores principales: | Pinto, Yishay, Gabay, Orshay, Arbiza, Leonardo, Sams, Aaron J., Keinan, Alon, Levanon, Erez Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864454/ https://www.ncbi.nlm.nih.gov/pubmed/27056836 http://dx.doi.org/10.1101/gr.199240.115 |
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