Human MAF1 targets and represses active RNA polymerase III genes by preventing recruitment rather than inducing long-term transcriptional arrest

RNA polymerase III (Pol III) is tightly controlled in response to environmental cues, yet a genomic-scale picture of Pol III regulation and the role played by its repressor MAF1 is lacking. Here, we describe genome-wide studies in human fibroblasts that reveal a dynamic and gene-specific adaptation...

Descripción completa

Detalles Bibliográficos
Autores principales: Orioli, Andrea, Praz, Viviane, Lhôte, Philippe, Hernandez, Nouria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864463/
https://www.ncbi.nlm.nih.gov/pubmed/26941251
http://dx.doi.org/10.1101/gr.201400.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864463/
https://www.ncbi.nlm.nih.gov/pubmed/26941251
http://dx.doi.org/10.1101/gr.201400.115

Ejemplares similares