Enhancer methylation dynamics contribute to cancer plasticity and patient mortality

During development, enhancers play pivotal roles in regulating gene expression programs; however, their involvement in cancer progression has not been fully characterized. We performed an integrative analysis of DNA methylation, RNA-seq, and small RNA-seq profiles from thousands of patients, includi...

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Detalles Bibliográficos
Autores principales: Bell, Rachel E., Golan, Tamar, Sheinboim, Danna, Malcov, Hagar, Amar, David, Salamon, Avi, Liron, Tamar, Gelfman, Sahar, Gabet, Yankel, Shamir, Ron, Levy, Carmit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864467/
https://www.ncbi.nlm.nih.gov/pubmed/26907635
http://dx.doi.org/10.1101/gr.197194.115

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