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Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes

BACKGROUND: Recent studies have implicated specific assembly subtypes of β-amyloid (Aβ) peptide, specifically soluble oligomers (soAβ) as disease-relevant structures that may underlie memory loss in Alzheimer disease. Removing existing soluble and insoluble Aβ assemblies is thought to be essential f...

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Detalles Bibliográficos
Autores principales:	Knight, Elysse M., Kim, Soong Ho, Kottwitz, Jessica C., Hatami, Asa, Albay, Ricardo, Suzuki, Akinobu, Lublin, Alex, Alberini, Cristina M., Klein, William L., Szabo, Paul, Relkin, Norman R., Ehrlich, Michelle, Glabe, Charles G., Gandy, Sam, Steele, John W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864617/ https://www.ncbi.nlm.nih.gov/pubmed/27218118 http://dx.doi.org/10.1212/NXI.0000000000000237

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