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Neutrophils drive accelerated tumor progression in the collagen-dense mammary tumor microenvironment
BACKGROUND: High mammographic density has been correlated with a 4-fold to 6-fold increased risk of developing breast cancer, and is associated with increased stromal deposition of extracellular matrix proteins, including collagen I. The molecular and cellular mechanisms responsible for high breast...
Autores principales: | García-Mendoza, María G., Inman, David R., Ponik, Suzanne M., Jeffery, Justin J., Sheerar, Dagna S., Van Doorn, Rachel R., Keely, Patricia J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864897/ https://www.ncbi.nlm.nih.gov/pubmed/27169366 http://dx.doi.org/10.1186/s13058-016-0703-7 |
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