Metformin prevents the effects of Pseudomonas aeruginosa on airway epithelial tight junctions and restricts hyperglycaemia‐induced bacterial growth

Lung disease and elevation of blood glucose are associated with increased glucose concentration in the airway surface liquid (ASL). Raised ASL glucose is associated with increased susceptibility to infection by respiratory pathogens including Staphylococcus aureus and Pseudomonas aeruginosa. We have...

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Detalles Bibliográficos
Autores principales: Patkee, Wishwanath R. A., Carr, Georgina, Baker, Emma H., Baines, Deborah L., Garnett, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864950/
https://www.ncbi.nlm.nih.gov/pubmed/26837005
http://dx.doi.org/10.1111/jcmm.12784

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