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Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development—Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Identifies a Strongly Associated Locus

Gliomas are the most common form of malignant primary brain tumors in humans and second most common in dogs, occurring with similar frequencies in both species. Dogs are valuable spontaneous models of human complex diseases including cancers and may provide insight into disease susceptibility and on...

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Detalles Bibliográficos
Autores principales: Truvé, Katarina, Dickinson, Peter, Xiong, Anqi, York, Daniel, Jayashankar, Kartika, Pielberg, Gerli, Koltookian, Michele, Murén, Eva, Fuxelius, Hans-Henrik, Weishaupt, Holger, Swartling, Fredrik J., Andersson, Göran, Hedhammar, Åke, Bongcam-Rudloff, Erik, Forsberg-Nilsson, Karin, Bannasch, Danika, Lindblad-Toh, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865040/
https://www.ncbi.nlm.nih.gov/pubmed/27171399
http://dx.doi.org/10.1371/journal.pgen.1006000