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Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development—Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Identifies a Strongly Associated Locus
Gliomas are the most common form of malignant primary brain tumors in humans and second most common in dogs, occurring with similar frequencies in both species. Dogs are valuable spontaneous models of human complex diseases including cancers and may provide insight into disease susceptibility and on...
Autores principales: | Truvé, Katarina, Dickinson, Peter, Xiong, Anqi, York, Daniel, Jayashankar, Kartika, Pielberg, Gerli, Koltookian, Michele, Murén, Eva, Fuxelius, Hans-Henrik, Weishaupt, Holger, Swartling, Fredrik J., Andersson, Göran, Hedhammar, Åke, Bongcam-Rudloff, Erik, Forsberg-Nilsson, Karin, Bannasch, Danika, Lindblad-Toh, Kerstin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865040/ https://www.ncbi.nlm.nih.gov/pubmed/27171399 http://dx.doi.org/10.1371/journal.pgen.1006000 |
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