Cargando…

A Novel ENU-Induced Mutation in Myo6 Causes Vestibular Dysfunction and Deafness

Mouse N-ethyl-N-nitrosourea (ENU) mutagenesis has generated many useful animal models for human diseases. Here we describe the identification of a novel ENU-induced mouse mutant strain Turner (Tur) that displays circling and headtossing behavior and progressive hearing loss. Tur/Tur homozygous anima...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Elaine Y. M., Xu, Chelsea Y., Brahmachary, Manisha, Xu, Pin-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865150/
https://www.ncbi.nlm.nih.gov/pubmed/27171474
http://dx.doi.org/10.1371/journal.pone.0154984