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Validation and Optimization of an Ex Vivo Assay of Intestinal Mucosal Biopsies in Crohn’s Disease: Reflects Inflammation and Drug Effects

Crohn’s disease (CD) is a chronic illness demanding better therapeutics. The marketed biologics only benefit some patients or elicit diminishing effect over time. To complement the known methods in drug development and to obtain patient specific drug responses, we optimized and validated a known hum...

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Detalles Bibliográficos
Autores principales:	Vadstrup, Kasper, Galsgaard, Elisabeth Douglas, Gerwien, Jens, Vester-Andersen, Marianne Kajbæk, Pedersen, Julie Steen, Rasmussen, Julie, Neermark, Søren, Kiszka-Kanowitz, Marianne, Jensen, Teis, Bendtsen, Flemming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865152/ https://www.ncbi.nlm.nih.gov/pubmed/27171179 http://dx.doi.org/10.1371/journal.pone.0155335

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