A Mouse Model for Conditional Secretion of Specific Single-Chain Antibodies Provides Genetic Evidence for Regulation of Cortical Plasticity by a Non-cell Autonomous Homeoprotein Transcription Factor

During postnatal life the cerebral cortex passes through critical periods of plasticity allowing its physiological adaptation to the environment. In the visual cortex, critical period onset and closure are influenced by the non-cell autonomous activity of the Otx2 homeoprotein transcription factor,...

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Detalles Bibliográficos
Autores principales: Bernard, Clémence, Vincent, Clémentine, Testa, Damien, Bertini, Eva, Ribot, Jérôme, Di Nardo, Ariel A., Volovitch, Michel, Prochiantz, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865174/
https://www.ncbi.nlm.nih.gov/pubmed/27171438
http://dx.doi.org/10.1371/journal.pgen.1006035

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