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ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway

Renal compensatory hypertrophy (RCH) restores normal kidney function after disease or loss of kidney tissue and is characterized by an increase in organ size due to cell enlargement and not to cell proliferation. In MDCK renal epithelial cells, silencing of the tight junction protein zona occludens...

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Detalles Bibliográficos
Autores principales:	Domínguez-Calderón, Alaide, Ávila-Flores, Antonia, Ponce, Arturo, López-Bayghen, Esther, Calderón-Salinas, José-Víctor, Luis Reyes, José, Chávez-Munguía, Bibiana, Segovia, José, Angulo, Carla, Ramírez, Leticia, Gallego-Gutiérrez, Helios, Alarcón, Lourdes, Martín-Tapia, Dolores, Bautista-García, Pablo, González-Mariscal, Lorenza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865316/ https://www.ncbi.nlm.nih.gov/pubmed/27009203 http://dx.doi.org/10.1091/mbc.E15-08-0598

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