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The novel RacE-binding protein GflB sharpens Ras activity at the leading edge of migrating cells
Directional sensing, a process in which cells convert an external chemical gradient into internal signaling events, is essential in chemotaxis. We previously showed that a Rho GTPase, RacE, regulates gradient sensing in Dictyostelium cells. Here, using affinity purification and mass spectrometry, we...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865317/ https://www.ncbi.nlm.nih.gov/pubmed/27009206 http://dx.doi.org/10.1091/mbc.E15-11-0796 |