Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer

ZNF322A encoding a classical Cys2His2 zinc finger transcription factor was previously revealed as a potential oncogene in lung cancer patients. However, the oncogenic role of ZNF322A and its underlying mechanism in lung tumorigenesis remain elusive. Here we show ZNF322A protein overexpression in 123...

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Detalles Bibliográficos
Autores principales: Jen, J, Lin, L-L, Chen, H-T, Liao, S-Y, Lo, F-Y, Tang, Y-A, Su, W-C, Salgia, R, Hsu, C-L, Huang, H-C, Juan, H-F, Wang, Y-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865475/
https://www.ncbi.nlm.nih.gov/pubmed/26279304
http://dx.doi.org/10.1038/onc.2015.296

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