Cargando…
Microarray data on altered transcriptional program of Phgdh-deficient mouse embryonic fibroblasts caused by ʟ-serine depletion
Inherent ʟ-Ser deficiency culminates in intrauterine growth retardation, severe malformation of multiple organs particularly the central nervous system, and perinatal or early postnatal death in human and mouse. To uncover the molecular mechanisms underlying the growth-arrested phenotypes of l-Ser d...
Autores principales: | Hamano, Momoko, Sayano, Tomoko, Kusada, Wataru, Kato, Hisanori, Furuya, Shigeki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865675/ https://www.ncbi.nlm.nih.gov/pubmed/27222860 http://dx.doi.org/10.1016/j.dib.2016.04.052 |
Ejemplares similares
-
Adaptive response to l‐serine deficiency is mediated by p38 MAPK activation via 1‐deoxysphinganine in normal fibroblasts
por: Sayano, Tomoko, et al.
Publicado: (2016) -
Enhanced vulnerability to oxidative stress and induction of inflammatory gene expression in 3‐phosphoglycerate dehydrogenase‐deficient fibroblasts
por: Hamano, Momoko, et al.
Publicado: (2018) -
Transcriptional Activation of Chac1 and Other Atf4-Target Genes Induced by Extracellular l-Serine Depletion is negated with Glycine Consumption in Hepa1-6 Hepatocarcinoma Cells
por: Hamano, Momoko, et al.
Publicado: (2020) -
Hepatocyte-Specific Phgdh-Deficient Mice Culminate in Mild Obesity, Insulin Resistance, and Enhanced Vulnerability to Protein Starvation
por: Hamano, Momoko, et al.
Publicado: (2021) -
Characterization of ETFDH and PHGDH Mutations in a Patient with Mild Glutaric Aciduria Type II and Serine Deficiency
por: Ali, Amanat, et al.
Publicado: (2021)