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Intraoperative indocyanine green angiography for the objective measurement of blood flow
PURPOSE: Intraoperative assessment of tissue perfusion is important to predict wound healing or improvement of symptoms in patients with peripheral arterial disease (PAD) or vascular trauma. There is no widely accepted standard for intraoperative measurement of tissue perfusion. Here, we report the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Surgical Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865706/ https://www.ncbi.nlm.nih.gov/pubmed/27186573 http://dx.doi.org/10.4174/astr.2016.90.5.279 |
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author | Joh, Jin Hyun Park, Ho-Chul Han, Sang-Ah Ahn, Hyung Joon |
author_facet | Joh, Jin Hyun Park, Ho-Chul Han, Sang-Ah Ahn, Hyung Joon |
author_sort | Joh, Jin Hyun |
collection | PubMed |
description | PURPOSE: Intraoperative assessment of tissue perfusion is important to predict wound healing or improvement of symptoms in patients with peripheral arterial disease (PAD) or vascular trauma. There is no widely accepted standard for intraoperative measurement of tissue perfusion. Here, we report the use of indocyanine green (ICG)-based angiography to determine the blood flow in patients with PAD and vascular trauma. METHODS: The SPY fluorescent imaging system was utilized. A dose of 3–5 mL of ICG (2.5 mg/mL) was injected intravenously followed by a 10 mL normal saline flush. The SPY imaging system was used to quantitatively assess perfusion. During the study period, the SPY imaging system was applied in 4 patients with PAD and one patient with vascular trauma. RESULTS: In 3 patients with PAD associated with an ischemic wound, complete wound healing was achieved with the indication of viable tissue by the SPY system. In one patient with severe claudication in both lower extremities, the ICG angiography was used to determine the increased blood flow after revascularization. In the case of vascular trauma, this imaging system enabled the delineation of viability of the injured tissue. CONCLUSION: ICG angiography can determine the surface tissue viability in PAD patients. In cases of severe vascular trauma,the SPY system can be used to determine tissue perfusion. Further study is warranted to define the definite utility of this technology to assess perfusion, response to revascularization, and potentially, to predict the likelihood of wound healing. |
format | Online Article Text |
id | pubmed-4865706 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Korean Surgical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-48657062016-05-16 Intraoperative indocyanine green angiography for the objective measurement of blood flow Joh, Jin Hyun Park, Ho-Chul Han, Sang-Ah Ahn, Hyung Joon Ann Surg Treat Res Original Article PURPOSE: Intraoperative assessment of tissue perfusion is important to predict wound healing or improvement of symptoms in patients with peripheral arterial disease (PAD) or vascular trauma. There is no widely accepted standard for intraoperative measurement of tissue perfusion. Here, we report the use of indocyanine green (ICG)-based angiography to determine the blood flow in patients with PAD and vascular trauma. METHODS: The SPY fluorescent imaging system was utilized. A dose of 3–5 mL of ICG (2.5 mg/mL) was injected intravenously followed by a 10 mL normal saline flush. The SPY imaging system was used to quantitatively assess perfusion. During the study period, the SPY imaging system was applied in 4 patients with PAD and one patient with vascular trauma. RESULTS: In 3 patients with PAD associated with an ischemic wound, complete wound healing was achieved with the indication of viable tissue by the SPY system. In one patient with severe claudication in both lower extremities, the ICG angiography was used to determine the increased blood flow after revascularization. In the case of vascular trauma, this imaging system enabled the delineation of viability of the injured tissue. CONCLUSION: ICG angiography can determine the surface tissue viability in PAD patients. In cases of severe vascular trauma,the SPY system can be used to determine tissue perfusion. Further study is warranted to define the definite utility of this technology to assess perfusion, response to revascularization, and potentially, to predict the likelihood of wound healing. The Korean Surgical Society 2016-05 2016-05-02 /pmc/articles/PMC4865706/ /pubmed/27186573 http://dx.doi.org/10.4174/astr.2016.90.5.279 Text en Copyright © 2016, the Korean Surgical Society http://creativecommons.org/licenses/by-nc/4.0/ Annals of Surgical Treatment and Research is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Joh, Jin Hyun Park, Ho-Chul Han, Sang-Ah Ahn, Hyung Joon Intraoperative indocyanine green angiography for the objective measurement of blood flow |
title | Intraoperative indocyanine green angiography for the objective measurement of blood flow |
title_full | Intraoperative indocyanine green angiography for the objective measurement of blood flow |
title_fullStr | Intraoperative indocyanine green angiography for the objective measurement of blood flow |
title_full_unstemmed | Intraoperative indocyanine green angiography for the objective measurement of blood flow |
title_short | Intraoperative indocyanine green angiography for the objective measurement of blood flow |
title_sort | intraoperative indocyanine green angiography for the objective measurement of blood flow |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865706/ https://www.ncbi.nlm.nih.gov/pubmed/27186573 http://dx.doi.org/10.4174/astr.2016.90.5.279 |
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