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Macrophage phagocytosis alters the MRI signal of ferumoxytol-labeled mesenchymal stromal cells in cartilage defects

Human mesenchymal stem cells (hMSCs) are a promising tool for cartilage regeneration in arthritic joints. hMSC labeling with iron oxide nanoparticles enables non-invasive in vivo monitoring of transplanted cells in cartilage defects with MR imaging. Since graft failure leads to macrophage phagocytos...

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Detalles Bibliográficos
Autores principales: Nejadnik, Hossein, Lenkov, Olga, Gassert, Florian, Fretwell, Deborah, Lam, Isaac, Daldrup-Link, Heike E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865731/
https://www.ncbi.nlm.nih.gov/pubmed/27174199
http://dx.doi.org/10.1038/srep25897