X-Ray Structure and Inhibition of 3C-like Protease from Porcine Epidemic Diarrhea Virus

Porcine epidemic diarrhea virus (PEDV) is a coronavirus that infects pigs and can have mortality rates approaching 100% in piglets, causing serious economic impact. The 3C-like protease (3CL(pro)) is essential for the coronaviral life cycle and is an appealing target for the development of therapeut...

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Detalles Bibliográficos
Autores principales: St. John, Sarah E., Anson, Brandon J., Mesecar, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865815/
https://www.ncbi.nlm.nih.gov/pubmed/27173881
http://dx.doi.org/10.1038/srep25961

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