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The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state

With about 350 million people chronically infected around the world hepatitis B is a major health problem. Template for progeny HBV synthesis is the viral genome, organized as a minichromosome (cccDNA) inside the hepatocyte nucleus. How viral cccDNA gene expression is regulated by its chromatin stru...

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Detalles Bibliográficos
Autores principales:	Alarcon, Valentina, Hernández, Sergio, Rubio, Lorena, Alvarez, Francisca, Flores, Yvo, Varas-Godoy, Manuel, De Ferrari, Giancarlo V., Kann, Michael, Villanueva, Rodrigo A., Loyola, Alejandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865824/ https://www.ncbi.nlm.nih.gov/pubmed/27174370 http://dx.doi.org/10.1038/srep25901

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