Putative histidine kinase inhibitors with antibacterial effect against multi-drug resistant clinical isolates identified by in vitro and in silico screens

Novel antibacterials are urgently needed to address the growing problem of bacterial resistance to conventional antibiotics. Two-component systems (TCS) are widely used by bacteria to regulate gene expression in response to various environmental stimuli and physiological stress and have been previou...

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Detalles Bibliográficos
Autores principales: Velikova, Nadya, Fulle, Simone, Manso, Ana Sousa, Mechkarska, Milena, Finn, Paul, Conlon, J. Michael, Oggioni, Marco Rinaldo, Wells, Jerry M., Marina, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865847/
https://www.ncbi.nlm.nih.gov/pubmed/27173778
http://dx.doi.org/10.1038/srep26085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865847/
https://www.ncbi.nlm.nih.gov/pubmed/27173778
http://dx.doi.org/10.1038/srep26085

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