CSF1R blockade slows the progression of amyotrophic lateral sclerosis by reducing microgliosis and invasion of macrophages into peripheral nerves

Inflammation is a common neuropathological feature in several neurological disorders, including amyotrophic lateral sclerosis (ALS). We have studied the contribution of CSF1R signalling to inflammation in ALS, as a pathway previously reported to control the expansion and activation of microglial cel...

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Detalles Bibliográficos
Autores principales: Martínez-Muriana, Anna, Mancuso, Renzo, Francos-Quijorna, Isaac, Olmos-Alonso, Adrian, Osta, Rosario, Perry, V. Hugh, Navarro, Xavier, Gomez-Nicola, Diego, López-Vales, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865981/
https://www.ncbi.nlm.nih.gov/pubmed/27174644
http://dx.doi.org/10.1038/srep25663

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