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The complete local genotype–phenotype landscape for the alternative splicing of a human exon
The properties of genotype–phenotype landscapes are crucial for understanding evolution but are not characterized for most traits. Here, we present a >95% complete local landscape for a defined molecular function—the alternative splicing of a human exon (FAS/CD95 exon 6, involved in the control o...
Autores principales: | Julien, Philippe, Miñana, Belén, Baeza-Centurion, Pablo, Valcárcel, Juan, Lehner, Ben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866304/ https://www.ncbi.nlm.nih.gov/pubmed/27161764 http://dx.doi.org/10.1038/ncomms11558 |
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