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Radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study

BACKGROUND: Radial endobronchial ultrasound with a guide sheath (EBUS-GS) has improved the diagnostic outcomes of peripheral lung lesions. However, to our knowledge, reports on the use of EBUS-GS for diagnosis of cavitary lesions are unavailable. Therefore, this study aimed to assess the effectivene...

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Autores principales: Hayama, Manabu, Okamoto, Norio, Suzuki, Hidekazu, Tamiya, Motohiro, Shiroyama, Takayuki, Tanaka, Ayako, Nishida, Takuji, Nishihara, Takashi, Uehara, Nobuko, Morishita, Naoko, Kawahara, Kunimitsu, Hirashima, Tomonori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866378/
https://www.ncbi.nlm.nih.gov/pubmed/27170169
http://dx.doi.org/10.1186/s12890-016-0244-y
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author Hayama, Manabu
Okamoto, Norio
Suzuki, Hidekazu
Tamiya, Motohiro
Shiroyama, Takayuki
Tanaka, Ayako
Nishida, Takuji
Nishihara, Takashi
Uehara, Nobuko
Morishita, Naoko
Kawahara, Kunimitsu
Hirashima, Tomonori
author_facet Hayama, Manabu
Okamoto, Norio
Suzuki, Hidekazu
Tamiya, Motohiro
Shiroyama, Takayuki
Tanaka, Ayako
Nishida, Takuji
Nishihara, Takashi
Uehara, Nobuko
Morishita, Naoko
Kawahara, Kunimitsu
Hirashima, Tomonori
author_sort Hayama, Manabu
collection PubMed
description BACKGROUND: Radial endobronchial ultrasound with a guide sheath (EBUS-GS) has improved the diagnostic outcomes of peripheral lung lesions. However, to our knowledge, reports on the use of EBUS-GS for diagnosis of cavitary lesions are unavailable. Therefore, this study aimed to assess the effectiveness and safety of EBUS-GS for diagnosis of peripheral cavitary lung lesions (PCLLs). METHODS: This study was a single-institution retrospective review of PCLLs examined by using EBUS-GS between July 2013 and October 2015. The diagnostic results of different EBUS-GS samples, including cytologic, histopathologic, and microbiologic samples, were analysed separately. RESULTS: Of 696 radial EBUS procedures performed during the study period, 50 were performed for examination of PCLLs. The overall diagnostic yield for EBUS-GS was 80 % (40/50). Regarding 27 malignant lesions, the diagnostic yields for cytologic and histopathologic samples were 63.0 % (17/27) and 74.1 % (20/27), respectively. Regarding 23 benign lesions, the diagnostic yields for histopathologic and microbiologic samples were 69.6 % (16/23) and 47.8 % (11/23), respectively. Uni- and multivariate analyses indicated that the EBUS probe being within the lesion was the only factor significantly associated with increased diagnostic yield (odds ratio, 7.04; P = 0.03). Although pulmonary infection occurred after the procedure in 1 patient (2.0 %), no other complications, including pneumothorax or significant haemorrhage, were reported. CONCLUSION: EBUS-GS was found to be an effective and safe procedure for diagnosis of PCLLs.
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spelling pubmed-48663782016-05-14 Radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study Hayama, Manabu Okamoto, Norio Suzuki, Hidekazu Tamiya, Motohiro Shiroyama, Takayuki Tanaka, Ayako Nishida, Takuji Nishihara, Takashi Uehara, Nobuko Morishita, Naoko Kawahara, Kunimitsu Hirashima, Tomonori BMC Pulm Med Research Article BACKGROUND: Radial endobronchial ultrasound with a guide sheath (EBUS-GS) has improved the diagnostic outcomes of peripheral lung lesions. However, to our knowledge, reports on the use of EBUS-GS for diagnosis of cavitary lesions are unavailable. Therefore, this study aimed to assess the effectiveness and safety of EBUS-GS for diagnosis of peripheral cavitary lung lesions (PCLLs). METHODS: This study was a single-institution retrospective review of PCLLs examined by using EBUS-GS between July 2013 and October 2015. The diagnostic results of different EBUS-GS samples, including cytologic, histopathologic, and microbiologic samples, were analysed separately. RESULTS: Of 696 radial EBUS procedures performed during the study period, 50 were performed for examination of PCLLs. The overall diagnostic yield for EBUS-GS was 80 % (40/50). Regarding 27 malignant lesions, the diagnostic yields for cytologic and histopathologic samples were 63.0 % (17/27) and 74.1 % (20/27), respectively. Regarding 23 benign lesions, the diagnostic yields for histopathologic and microbiologic samples were 69.6 % (16/23) and 47.8 % (11/23), respectively. Uni- and multivariate analyses indicated that the EBUS probe being within the lesion was the only factor significantly associated with increased diagnostic yield (odds ratio, 7.04; P = 0.03). Although pulmonary infection occurred after the procedure in 1 patient (2.0 %), no other complications, including pneumothorax or significant haemorrhage, were reported. CONCLUSION: EBUS-GS was found to be an effective and safe procedure for diagnosis of PCLLs. BioMed Central 2016-05-11 /pmc/articles/PMC4866378/ /pubmed/27170169 http://dx.doi.org/10.1186/s12890-016-0244-y Text en © Hayama et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Hayama, Manabu
Okamoto, Norio
Suzuki, Hidekazu
Tamiya, Motohiro
Shiroyama, Takayuki
Tanaka, Ayako
Nishida, Takuji
Nishihara, Takashi
Uehara, Nobuko
Morishita, Naoko
Kawahara, Kunimitsu
Hirashima, Tomonori
Radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study
title Radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study
title_full Radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study
title_fullStr Radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study
title_full_unstemmed Radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study
title_short Radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study
title_sort radial endobronchial ultrasound with a guide sheath for diagnosis of peripheral cavitary lung lesions: a retrospective study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866378/
https://www.ncbi.nlm.nih.gov/pubmed/27170169
http://dx.doi.org/10.1186/s12890-016-0244-y
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