Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and dihydroxyvitamin D3 (VD3)-induced HL-60 cells differentiation

BACKGROUND: Lyn, an import member of Src family kinases (SFKs), is supposed to be implicated in acute myeloid leukemia (AML) pathogenesis and development by participation in AML differentiation, yet the details still remain incompletely understood. The expression status of Lyn and its correlation wi...

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Detalles Bibliográficos
Autores principales: Iriyama, Noriyoshi, Yuan, Bo, Hatta, Yoshihiro, Takagi, Norio, Takei, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866426/
https://www.ncbi.nlm.nih.gov/pubmed/27182202
http://dx.doi.org/10.1186/s12935-016-0314-5

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