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Neuroimaging basis in the conversion of aMCI patients with APOE-ε4 to AD: study protocol of a prospective diagnostic trial

BACKGROUND: The ε4 allele of the Apolipoprotein E gene (APOE-ε4) is a potent genetic risk factor for sporadic Alzheimer’s disease (AD). Amnestic mild cognitive impairment (aMCI) is an intermediate state between normal cognitive aging and dementia, which is easy to convert to AD dementia. It is an ur...

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Detalles Bibliográficos
Autores principales:	Chen, Guan-Qun, Sheng, Can, Li, Yu-Xia, Yu, Yang, Wang, Xiao-Ni, Sun, Yu, Li, Hong-Yan, Li, Xuan-Yu, Xie, Yun-Yan, Han, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866435/ https://www.ncbi.nlm.nih.gov/pubmed/27176479 http://dx.doi.org/10.1186/s12883-016-0587-2

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