Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS

Annonaceous acetogenins (AAGs) are environmental neurotoxins from the fruit pulp of several Annonaceae species, whose consumption was linked to the occurrence of sporadic atypical Parkinsonism with dementia. The quantification of the prototypical AAG annonacin in Rat brain homogenates was performed...

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Autores principales: Bonneau, Natacha, Schmitz-Afonso, Isabelle, Brunelle, Alain, Touboul, David, Champy, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866534/
https://www.ncbi.nlm.nih.gov/pubmed/27222866
http://dx.doi.org/10.1016/j.dib.2016.04.067
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author Bonneau, Natacha
Schmitz-Afonso, Isabelle
Brunelle, Alain
Touboul, David
Champy, Pierre
author_facet Bonneau, Natacha
Schmitz-Afonso, Isabelle
Brunelle, Alain
Touboul, David
Champy, Pierre
author_sort Bonneau, Natacha
collection PubMed
description Annonaceous acetogenins (AAGs) are environmental neurotoxins from the fruit pulp of several Annonaceae species, whose consumption was linked to the occurrence of sporadic atypical Parkinsonism with dementia. The quantification of the prototypical AAG annonacin in Rat brain homogenates was performed by UPLC-MS/MS in selected reaction monitoring (SRM) mode, using a triple quadrupole mass analyzer. A natural analog of annonacin was used as an internal standard. Analyzed data set of the analytical validation of this method is presented, including stability of the samples, extraction recovery and matrix effect, supporting the results described in the article “Quantification of the environmental neurotoxin annonacin in Rat brain by UPLC-MS/MS” N. Bonneau, I. Schmitz-Afonso, D. Touboul, A. Brunelle, P. Champy (2016) [1].
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spelling pubmed-48665342016-05-24 Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS Bonneau, Natacha Schmitz-Afonso, Isabelle Brunelle, Alain Touboul, David Champy, Pierre Data Brief Data Article Annonaceous acetogenins (AAGs) are environmental neurotoxins from the fruit pulp of several Annonaceae species, whose consumption was linked to the occurrence of sporadic atypical Parkinsonism with dementia. The quantification of the prototypical AAG annonacin in Rat brain homogenates was performed by UPLC-MS/MS in selected reaction monitoring (SRM) mode, using a triple quadrupole mass analyzer. A natural analog of annonacin was used as an internal standard. Analyzed data set of the analytical validation of this method is presented, including stability of the samples, extraction recovery and matrix effect, supporting the results described in the article “Quantification of the environmental neurotoxin annonacin in Rat brain by UPLC-MS/MS” N. Bonneau, I. Schmitz-Afonso, D. Touboul, A. Brunelle, P. Champy (2016) [1]. Elsevier 2016-05-04 /pmc/articles/PMC4866534/ /pubmed/27222866 http://dx.doi.org/10.1016/j.dib.2016.04.067 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Bonneau, Natacha
Schmitz-Afonso, Isabelle
Brunelle, Alain
Touboul, David
Champy, Pierre
Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS
title Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS
title_full Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS
title_fullStr Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS
title_full_unstemmed Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS
title_short Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS
title_sort validation data for the quantification of the annonaceous acetogenin annonacin in rat brain by uplc-ms/ms
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866534/
https://www.ncbi.nlm.nih.gov/pubmed/27222866
http://dx.doi.org/10.1016/j.dib.2016.04.067
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