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DNA Editing of LTR Retrotransposons Reveals the Impact of APOBECs on Vertebrate Genomes
Long terminal repeat retrotransposons (LTR) are widespread in vertebrates and their dynamism facilitates genome evolution. However, these endogenous retroviruses (ERVs) must be restricted to maintain genomic stability. The APOBECs, a protein family that can edit C-to-U in DNA, do so by interfering w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866542/ https://www.ncbi.nlm.nih.gov/pubmed/26541172 http://dx.doi.org/10.1093/molbev/msv239 |