Development of micro-fibrous solid dispersions of poorly water-soluble drugs in sucrose using temperature-controlled centrifugal spinning

Solid dispersion technology represents a successful approach to addressing the bioavailability issues caused by the low aqueous solubility of many Biopharmaceutics Classification System (BCS) Class II drugs. In this study, the use of high-yield manufacture of fiber-based dispersion is explored as an...

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Detalles Bibliográficos
Autores principales: Marano, Stefania, Barker, Susan Anne, Raimi-Abraham, Bahijja Tolulope, Missaghi, Shahrzad, Rajabi-Siahboomi, Ali, Craig, Duncan Q.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866555/
https://www.ncbi.nlm.nih.gov/pubmed/27012901
http://dx.doi.org/10.1016/j.ejpb.2016.03.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866555/
https://www.ncbi.nlm.nih.gov/pubmed/27012901
http://dx.doi.org/10.1016/j.ejpb.2016.03.021

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