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Effect of LXR/RXR agonism on brain and CSF Aβ40 levels in rats

Alzheimer's disease (AD) is characterized pathologically by the presence of amyloid plaques and neurofibrillary tangles. The amyloid hypothesis contends that the abnormal accumulation of Aβ, the principal component of amyloid plaques, plays an essential role in initiating the disease. Impaired...

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Detalles Bibliográficos
Autores principales: Wang, Songli, Wen, Paul, Wood, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866632/
https://www.ncbi.nlm.nih.gov/pubmed/27239272
http://dx.doi.org/10.12688/f1000research.7868.2