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Effect of LXR/RXR agonism on brain and CSF Aβ40 levels in rats
Alzheimer's disease (AD) is characterized pathologically by the presence of amyloid plaques and neurofibrillary tangles. The amyloid hypothesis contends that the abnormal accumulation of Aβ, the principal component of amyloid plaques, plays an essential role in initiating the disease. Impaired...
Autores principales: | Wang, Songli, Wen, Paul, Wood, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866632/ https://www.ncbi.nlm.nih.gov/pubmed/27239272 http://dx.doi.org/10.12688/f1000research.7868.2 |
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