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Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity
Smooth muscle alpha-actin (SMA) is a marker for the contractile, non-proliferative phenotype of adult smooth muscle cells (SMCs). Upon arterial injury, expression of SMA and other structural proteins decreases and SMCs acquire a pro-migratory and proliferative phenotype. To what extent SMA regulates...
Autores principales: | Chen, Lihua, DeWispelaere, Allison, Dastvan, Frank, Osborne, William R. A., Blechner, Christine, Windhorst, Sabine, Daum, Guenter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866761/ https://www.ncbi.nlm.nih.gov/pubmed/27176050 http://dx.doi.org/10.1371/journal.pone.0155726 |
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