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High Persister Mutants in Mycobacterium tuberculosis
Mycobacterium tuberculosis forms drug-tolerant persister cells that are the probable cause of its recalcitrance to antibiotic therapy. While genetically identical to the rest of the population, persisters are dormant, which protects them from killing by bactericidal antibiotics. The mechanism of per...
Autores principales: | Torrey, Heather L., Keren, Iris, Via, Laura E., Lee, Jong Seok, Lewis, Kim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866775/ https://www.ncbi.nlm.nih.gov/pubmed/27176494 http://dx.doi.org/10.1371/journal.pone.0155127 |
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