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Evolution of the α-Subunit of Na/K-ATPase from Paramecium to Homo sapiens: Invariance of Transmembrane Helix Topology

Na/K-ATPase is a key plasma membrane enzyme involved in cell signaling, volume regulation, and maintenance of electrochemical gradients. The α-subunit, central to these functions, belongs to a large family of P-type ATPases. Differences in transmembrane (TM) helix topology, sequence homology, helix–...

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Detalles Bibliográficos
Autores principales: Morrill, Gene A., Kostellow, Adele B., Liu, Lijun, Gupta, Raj K., Askari, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866997/
https://www.ncbi.nlm.nih.gov/pubmed/26961431
http://dx.doi.org/10.1007/s00239-016-9732-1