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Precision Targeted Mutagenesis via Cas9 Paired Nickases in Rice

Recent reports of CRISPR- (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) mediated heritable mutagenesis in plants highlight the need for accuracy of the mutagenesis directed by this system. Off-target mutations are an important issue when considering f...

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Detalles Bibliográficos
Autores principales:	Mikami, Masafumi, Toki, Seiichi, Endo, Masaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Regular Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867050/ https://www.ncbi.nlm.nih.gov/pubmed/26936792 http://dx.doi.org/10.1093/pcp/pcw049

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