Intestinal-specific activatable Myb initiates colon tumorigenesis in mice

Transcription factor Myb is overexpressed in most colorectal cancers (CRC). Patients with CRC expressing the highest Myb are more likely to relapse. We previously showed that mono-allelic loss of Myb in an Adenomatous polyposis coli (APC)-driven CRC mouse model (Apc(Min/+)) significantly improves su...

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Detalles Bibliográficos
Autores principales: Malaterre, J, Pereira, L, Putoczki, T, Millen, R, Paquet-Fifield, S, Germann, M, Liu, J, Cheasley, D, Sampurno, S, Stacker, S A, Achen, M G, Ward, R L, Waring, P, Mantamadiotis, T, Ernst, M, Ramsay, R G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867492/
https://www.ncbi.nlm.nih.gov/pubmed/26300002
http://dx.doi.org/10.1038/onc.2015.305

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