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Decreased expression of hyaluronan synthase 1 and 2 associates with poor prognosis in cutaneous melanoma

BACKGROUND: Hyaluronan is a large extracellular matrix molecule involved in several biological processes such as proliferation, migration and invasion. In many cancers, hyaluronan synthesis is altered, which implicates disease progression and metastatic potential. We have previously shown that synth...

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Detalles Bibliográficos
Autores principales: Poukka, Mari, Bykachev, Andrey, Siiskonen, Hanna, Tyynelä-Korhonen, Kristiina, Auvinen, Päivi, Pasonen-Seppänen, Sanna, Sironen, Reijo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867536/
https://www.ncbi.nlm.nih.gov/pubmed/27184066
http://dx.doi.org/10.1186/s12885-016-2344-8