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Decreased expression of hyaluronan synthase 1 and 2 associates with poor prognosis in cutaneous melanoma
BACKGROUND: Hyaluronan is a large extracellular matrix molecule involved in several biological processes such as proliferation, migration and invasion. In many cancers, hyaluronan synthesis is altered, which implicates disease progression and metastatic potential. We have previously shown that synth...
Autores principales: | Poukka, Mari, Bykachev, Andrey, Siiskonen, Hanna, Tyynelä-Korhonen, Kristiina, Auvinen, Päivi, Pasonen-Seppänen, Sanna, Sironen, Reijo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867536/ https://www.ncbi.nlm.nih.gov/pubmed/27184066 http://dx.doi.org/10.1186/s12885-016-2344-8 |
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