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Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS

The fatal disease amyotrophic lateral sclerosis (ALS) is characterized by the loss of somatic motor neurons leading to muscle wasting and paralysis. However, motor neurons in the oculomotor nucleus, controlling eye movement, are for unknown reasons spared. We found that insulin-like growth factor 2...

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Detalles Bibliográficos
Autores principales:	Allodi, Ilary, Comley, Laura, Nichterwitz, Susanne, Nizzardo, Monica, Simone, Chiara, Benitez, Julio Aguila, Cao, Ming, Corti, Stefania, Hedlund, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867585/ https://www.ncbi.nlm.nih.gov/pubmed/27180807 http://dx.doi.org/10.1038/srep25960

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