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Impaired Nitric Oxide Mediated Vasodilation In The Peripheral Circulation In The R6/2 Mouse Model Of Huntington’s Disease

Recent evidence shows that the Huntington’s disease (HD) extends beyond the nervous system to other sites, including the cardiovascular system. Further, the cardiovascular pathology pre-dates neurological decline, however the mechanisms involved remain unclear. We investigated in the R6/2 mouse mode...

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Detalles Bibliográficos
Autores principales: Kane, Andrew D., Niu, Youguo, Herrera, Emilio A., Morton, A. Jennifer, Giussani, Dino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867587/
https://www.ncbi.nlm.nih.gov/pubmed/27181166
http://dx.doi.org/10.1038/srep25979