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Impaired Nitric Oxide Mediated Vasodilation In The Peripheral Circulation In The R6/2 Mouse Model Of Huntington’s Disease
Recent evidence shows that the Huntington’s disease (HD) extends beyond the nervous system to other sites, including the cardiovascular system. Further, the cardiovascular pathology pre-dates neurological decline, however the mechanisms involved remain unclear. We investigated in the R6/2 mouse mode...
Autores principales: | Kane, Andrew D., Niu, Youguo, Herrera, Emilio A., Morton, A. Jennifer, Giussani, Dino A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867587/ https://www.ncbi.nlm.nih.gov/pubmed/27181166 http://dx.doi.org/10.1038/srep25979 |
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