An early granulocyte colony-stimulating factor treatment attenuates neuropathic pain through activation of mu opioid receptors on the injured nerve

Several studies have shown that the mu opioid receptor (MOR) located in the peripheral nerves can be activated after nerve injury and that it attenuates peripheral nociceptive signals to the spinal dorsal horn. Various cytokines and phosphorylated-p38 (p-p38) activation in the dorsal horn also play...

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Detalles Bibliográficos
Autores principales: Liao, Ming-Feng, Yeh, Shin-Rung, Lo, Ai-Lun, Chao, Po-Kuan, Lee, Yun-Lin, Hung, Yu-Hui, Lu, Kwok-Tung, Ro, Long-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867617/
https://www.ncbi.nlm.nih.gov/pubmed/27180600
http://dx.doi.org/10.1038/srep25490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867617/
https://www.ncbi.nlm.nih.gov/pubmed/27180600
http://dx.doi.org/10.1038/srep25490

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