New use for an old drug: COX‐independent anti‐inflammatory effects of sulindac in models of cystic fibrosis

BACKGROUND AND PURPOSE: Pulmonary disease is the main cause of morbidity and mortality in cystic fibrosis (CF) patients due to exacerbated inflammation. To date, the only anti‐inflammatory drug available to CF patients is high‐dose ibuprofen, which can slow pulmonary disease progression, but whose c...

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Detalles Bibliográficos
Autores principales: Rocca, Jérémy, Manin, Sylvie, Hulin, Anne, Aissat, Abdel, Verbecq‐Morlot, Wilfried, Prulière‐Escabasse, Virginie, Wohlhuter‐Haddad, Adeline, Epaud, Ralph, Fanen, Pascale, Tarze, Agathe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867744/
https://www.ncbi.nlm.nih.gov/pubmed/26894321
http://dx.doi.org/10.1111/bph.13464

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