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Tumor-associated fibroblasts promote the proliferation and decrease the doxorubicin sensitivity of liposarcoma cells
The reasons for the distinct chemoresistance of liposarcomas and their high risk of local recurrence still remain unclear. Depending on the histological subtype of liposarcoma, first-line therapy with the cytostatic agent, doxorubicin, only achieves response rates of approximately 36%. Approximatley...
Autores principales: | HARATI, KAMRAN, DAIGELER, ADRIEN, HIRSCH, TOBIAS, JACOBSEN, FRANK, BEHR, BJÖRN, WALLNER, CHRISTOPH, LEHNHARDT, MARCUS, BECERIKLI, MUSTAFA |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867885/ https://www.ncbi.nlm.nih.gov/pubmed/27082154 http://dx.doi.org/10.3892/ijmm.2016.2556 |
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