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Acute outcome of treating patients admitted with electrical storm in a tertiary care centre

BACKGROUND: Electrical storm (ES) is a life threatening emergency. There is little data available regarding acute outcome of ES. AIMS: The study aimed to analyze the acute outcome of ES, various treatment modalities used, and the factors associated with mortality. METHODS: This is a retrospective ob...

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Autores principales: Prabhu, Mukund A., Namboodiri, Narayanan, Prasad BV, Srinivas, Abhilash, S.P., Thajudeen, Anees, Ajith, Kumar V.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867964/
https://www.ncbi.nlm.nih.gov/pubmed/27479203
http://dx.doi.org/10.1016/j.ipej.2016.03.002
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author Prabhu, Mukund A.
Namboodiri, Narayanan
Prasad BV, Srinivas
Abhilash, S.P.
Thajudeen, Anees
Ajith, Kumar V.K.
author_facet Prabhu, Mukund A.
Namboodiri, Narayanan
Prasad BV, Srinivas
Abhilash, S.P.
Thajudeen, Anees
Ajith, Kumar V.K.
author_sort Prabhu, Mukund A.
collection PubMed
description BACKGROUND: Electrical storm (ES) is a life threatening emergency. There is little data available regarding acute outcome of ES. AIMS: The study aimed to analyze the acute outcome of ES, various treatment modalities used, and the factors associated with mortality. METHODS: This is a retrospective observational study involving patients admitted with ES at our centre between 1/1/2007 and 31/12/2013. RESULTS: 41 patients (mean age 54.61 ± 12.41 years; 86.7% males; mean ejection fraction (EF) 44.51 ± 16.48%) underwent treatment for ES. Hypokalemia (14.63%) and acute coronary syndrome (ACS) (14.63%) were the commonest identifiable triggers. Only 9 (21.95%) patients already had an ICD implanted. Apart from antiarrhythmic drugs (100%), deep sedation (87.8%), mechanical ventilation (24.39%) and neuraxial modulation using left sympathetic cardiac denervation (21.95%) were the common treatment modalities used. Thirty-three (80.49%) patients could be discharged after a mean duration of 14.2 ± 2.31 days. Eight (19.5%) patients died in hospital. The mortality was significantly higher in those with EF < 35% compared to those with a higher EF (8 (42.11% vs 0 (0%), p = 0.03)). There was no significant difference in mortality between those with versus without a structural heart disease (8 (21.1% vs 0 (0%), p = 0.32)). Comparison of mortality an ACS with ES versus ES of other aetiologies (3 (50%) vs 5 (14.29) %, p = 0.076)) showed a trend towards significance. CONCLUSION: With comprehensive treatment, there is reasonable acute survival rate of ES. Hypokalemia and ACS are the commonest triggers of ES. Patients with low EF and ACS have higher mortality.
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spelling pubmed-48679642016-06-02 Acute outcome of treating patients admitted with electrical storm in a tertiary care centre Prabhu, Mukund A. Namboodiri, Narayanan Prasad BV, Srinivas Abhilash, S.P. Thajudeen, Anees Ajith, Kumar V.K. Indian Pacing Electrophysiol J Original Article BACKGROUND: Electrical storm (ES) is a life threatening emergency. There is little data available regarding acute outcome of ES. AIMS: The study aimed to analyze the acute outcome of ES, various treatment modalities used, and the factors associated with mortality. METHODS: This is a retrospective observational study involving patients admitted with ES at our centre between 1/1/2007 and 31/12/2013. RESULTS: 41 patients (mean age 54.61 ± 12.41 years; 86.7% males; mean ejection fraction (EF) 44.51 ± 16.48%) underwent treatment for ES. Hypokalemia (14.63%) and acute coronary syndrome (ACS) (14.63%) were the commonest identifiable triggers. Only 9 (21.95%) patients already had an ICD implanted. Apart from antiarrhythmic drugs (100%), deep sedation (87.8%), mechanical ventilation (24.39%) and neuraxial modulation using left sympathetic cardiac denervation (21.95%) were the common treatment modalities used. Thirty-three (80.49%) patients could be discharged after a mean duration of 14.2 ± 2.31 days. Eight (19.5%) patients died in hospital. The mortality was significantly higher in those with EF < 35% compared to those with a higher EF (8 (42.11% vs 0 (0%), p = 0.03)). There was no significant difference in mortality between those with versus without a structural heart disease (8 (21.1% vs 0 (0%), p = 0.32)). Comparison of mortality an ACS with ES versus ES of other aetiologies (3 (50%) vs 5 (14.29) %, p = 0.076)) showed a trend towards significance. CONCLUSION: With comprehensive treatment, there is reasonable acute survival rate of ES. Hypokalemia and ACS are the commonest triggers of ES. Patients with low EF and ACS have higher mortality. Elsevier 2016-03-29 /pmc/articles/PMC4867964/ /pubmed/27479203 http://dx.doi.org/10.1016/j.ipej.2016.03.002 Text en Copyright © 2016, Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.
spellingShingle Original Article
Prabhu, Mukund A.
Namboodiri, Narayanan
Prasad BV, Srinivas
Abhilash, S.P.
Thajudeen, Anees
Ajith, Kumar V.K.
Acute outcome of treating patients admitted with electrical storm in a tertiary care centre
title Acute outcome of treating patients admitted with electrical storm in a tertiary care centre
title_full Acute outcome of treating patients admitted with electrical storm in a tertiary care centre
title_fullStr Acute outcome of treating patients admitted with electrical storm in a tertiary care centre
title_full_unstemmed Acute outcome of treating patients admitted with electrical storm in a tertiary care centre
title_short Acute outcome of treating patients admitted with electrical storm in a tertiary care centre
title_sort acute outcome of treating patients admitted with electrical storm in a tertiary care centre
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867964/
https://www.ncbi.nlm.nih.gov/pubmed/27479203
http://dx.doi.org/10.1016/j.ipej.2016.03.002
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