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CD24 cell surface expression in Mvt1 mammary cancer cells serves as a biomarker for sensitivity to anti-IGF1R therapy
BACKGROUND: The pro-tumorigenic effects of the insulin-like growth factor receptor (IGF1R) are well described. IGF1R promotes cancer cell survival and proliferation and prevents apoptosis, and, additionally it was shown that IGF1R levels are significantly elevated in most common human malignancies i...
Autores principales: | Rostoker, Ran, Ben-Shmuel, Sarit, Rashed, Rola, Shen Orr, Zila, LeRoith, Derek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867988/ https://www.ncbi.nlm.nih.gov/pubmed/27179633 http://dx.doi.org/10.1186/s13058-016-0711-7 |
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