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OTO-201: Nonclinical Assessment of a Sustained-Release Ciprofloxacin Hydrogel for the Treatment of Otitis Media
HYPOTHESIS: OTO-201 can provide sustained release to the middle ear and effectively treat otitis media, when compared with FDA-approved ciprofloxacin otic drop formulations. BACKGROUND: There is an unmet medical need for antibiotic therapy that can provide a full course of treatment from a single ad...
Autores principales: | Wang, Xiaobo, Fernandez, Rayne, Tsivkovskaia, Natalia, Harrop-Jones, Anne, Hou, Huiying J., Dellamary, Luis, Dolan, David F., Altschuler, Richard A., LeBel, Carl, Piu, Fabrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867991/ https://www.ncbi.nlm.nih.gov/pubmed/24518407 http://dx.doi.org/10.1097/MAO.0000000000000261 |
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