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Transfer of malignant trait to BRCA1 deficient human fibroblasts following exposure to serum of cancer patients
BACKGROUND: It was reported that metastases might occur via transfer of biologically active blood circulating molecules from the primary tumor to distant organs rather than only migration of cancer cells. We showed in an earlier study that exposure of immortalized human embryonic kidney cells (HEK 2...
Autores principales: | Hamam, Dana, Abdouh, Mohamed, Gao, Zu-Hua, Arena, Vincenzo, Arena, Manuel, Arena, Goffredo Orazio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868000/ https://www.ncbi.nlm.nih.gov/pubmed/27179759 http://dx.doi.org/10.1186/s13046-016-0360-9 |
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