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Frequencies of CYP2C9 polymorphisms in North Indian population and their association with drug levels in children on phenytoin monotherapy

BACKGROUND: Phenytoin, mainly metabolized by cytochrome P450 enzyme system, has a narrow therapeutic index and may have adverse effects due to inter-individual variation in the dose requirement and genetic polymorphisms. This cross-sectional study was done to study the prevalence of cytochrome P450...

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Detalles Bibliográficos
Autores principales:	Chaudhary, Nagendra, Kabra, Madhulika, Gulati, Sheffali, Gupta, Yogendra Kumar, Pandey, Ravindra Mohan, Bhatia, Bal Dev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868001/ https://www.ncbi.nlm.nih.gov/pubmed/27179628 http://dx.doi.org/10.1186/s12887-016-0603-0

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