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Combinatory effect of BRCA1 and HERC2 expression on outcome in advanced non-small-cell lung cancer

BACKGROUND: BRCA1 is a main component of homologous recombination and induces resistance to platinum in preclinical models. It has been studied as a potential predictive marker in lung cancer. Several proteins modulate the function of BRCA1. The E3 ubiquitin ligase HERC2 facilitates the assembly of...

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Detalles Bibliográficos
Autores principales:	Bonanno, Laura, Costa, Carlota, Majem, Margarita, Sanchez, Jose-Javier, Rodriguez, Ignacio, Gimenez-Capitan, Ana, Molina-Vila, Miquel Angel, Vergnenegre, Alain, Massuti, Bartomeu, Favaretto, Adolfo, Rugge, Massimo, Pallares, Cinta, Taron, Miquel, Rosell, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868003/ https://www.ncbi.nlm.nih.gov/pubmed/27179511 http://dx.doi.org/10.1186/s12885-016-2339-5

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